Generic Chloroquine: Dosage and Interactions

Characteristic	Details
Common Brand Name	Aralen
Available Dosages	250 mg, 500 mg
Active Ingredient	Chloroquine Phosphate
Learn More About Generic Chloroquine

Common Brand Name

Generic Chloroquine, commonly known under the brand name Aralen, is an antimalarial medication. Primarily used to prevent and treat malaria, it exhibits anti-inflammatory properties, contributing to its use in autoimmune conditions such as rheumatoid arthritis and lupus. The active ingredient in this drug, chloroquine phosphate, is renowned for its effectiveness.

Aralen has been the mainstay in malaria prophylaxis for decades. Despite newer alternatives, it remains critical in areas with specific malaria strains. Its mechanism of action involves interference with the growth of parasites in the red blood cells.

Dosage Information

Generic Chloroquine is available in tablet form, typically as 250 mg or 500 mg dosages. The standard dose for malaria prevention is 500 mg once a week. Start taking it one to two weeks before entering a malarial area and continue for four weeks after leaving.

For treating acute malaria, the initial dose often involves a larger amount followed by smaller doses over the next few days. Compliance with dosing schedules ensures the medication’s efficacy and minimizes the risk of resistance.

Warning & Precautions

Before initiating chloroquine, a thorough assessment of patient history is crucial. Patients with known retinal or visual field changes must avoid this medication. Regular eye exams are essential for those on long-term therapy.

Caution is advised in individuals with liver disease, psoriasis, or glucose-6-phosphate dehydrogenase deficiency. A baseline ECG may be prudent due to the potential for cardiac side effects, especially in high doses.

Generic Chloroquine Interactions

Concurrent use with other drugs requires vigilance. Chloroquine interacts with medications like cyclosporine, increasing the risk of side effects. Antacids may reduce its absorption, necessitating administration timing adjustment.

When combined with medications that prolong the QT interval, such as certain antiarrhythmics, the risk of arrhythmia increases. Mayo Clinic provides a comprehensive list of potential drug interactions.

Generic Chloroquine Signs and Symptoms of Overdose

Overdose is a critical situation with potentially life-threatening consequences. Symptoms may manifest rapidly, including headache, drowsiness, nausea, visual disturbances, and cardiovascular collapse.

Prompt medical attention is essential. Treatment is supportive, emphasizing airway management and seizure control. Activated charcoal may be beneficial if administered quickly.

Is Non-Prescription Generic Chloroquine Available?

Chloroquine requires a prescription, ensuring it is used under medical supervision. Unregulated access may lead to misuse and serious side effects. Purchasing from unauthorized sources risks obtaining substandard or counterfeit products.

Patients must consult healthcare providers to obtain this medication. Ensuring its appropriate use is crucial for safety and efficacy. Trusting licensed professionals safeguards against adverse outcomes.

Attribute	Details
Legal Status	Prescription Only
Formulation	Tablet
Risk Factors	Visual impairment, liver disease

Malaria Prevention
Autoimmune Disorders
Rheumatoid Arthritis
Lupus

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